Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
Detaillierte Hinweise zur Methadontabletten zur Schmerzbehandlung
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Prescribers should always follow appropriate pain management principles of careful assessment and ongoing monitoring.
Several factors complicate the Deutung of investigations of the children of women World health organization take methadone during pregnancy. These include the maternal use of illicit drugs, other maternal factors such as nutrition, infection, and psychosocial circumstances, limited information regarding dose and duration of methadone use during pregnancy, and the fact that most maternal exposure appears to occur after the first trimester of pregnancy. Hinein addition, reported studies generally compare the benefit of methadone to the risk of untreated addiction to illicit drugs; the relevance of these findings to pain patients prescribed methadone during pregnancy is unclear.
Accidental or deliberate ingestion by a child may cause respiratory depression that can result rein death. Patients and caregivers should be instructed to keep methadone hinein a secure place out of the reach of children and to discard unused methadone in such a way that individuals other than the patient for whom it was originally prescribed will not come in contact with the drug.
Selection of patients for treatment with methadone should Beryllium governed by the same principles that apply to the use of other opioids (Teich INDICATIONS AND USAGE).
The total daily dose, potency and specific characteristics of the opioid the patient had been taking previously, if any;
Since methadone is lipophilic, it has been known to persist hinein the liver and other tissues. The slow release from the liver and other tissues may prolong the duration of methadone action despite low plasma concentrations.
Fertility – Reproductive function hinein human males may be decreased by methadone treatment. Reductions hinein ejaculate volume and seminal vesicle and prostate secretions have been reported rein methadone-treated individuals. Rein addition, reductions rein serum testosterone levels and sperm motility, and abnormalities rein sperm morphology have been reported. Published animal studies provide additional data indicating that methadone treatment of males can alter reproductive function.
Based on an average milk consumption of 150 mL/kg/day, an infant would consume approximately 17.4 mcg/kg/day which is approximately 2 to 3% of the oral maternal dose. Methadone has been detected in very low plasma concentrations hinein some infants whose mothers were taking methadone. Women on high-dose methadone maintenance, Weltgesundheitsorganisation are already breast-feeding, should Beryllium counseled to wean breast-feeding gradually hinein order to prevent neonatal abstinence syndrome.
Do not take any medicine while using methadone hydrochloride tablets until you have first talked to your doctor or pharmacist. They will Beryllium able to tell you if it is safe to take other medicines while you are using methadone hydrochloride tablets.
In using methadone an individualized benefit to risk assessment should Beryllium carried out and should include evaluation of patient presentation and complete medical history.
Methadone is a prescription drug. It’s an opioid, which makes it a controlled substance. This means this drug has a risk of misuse and may cause dependence.
Methadone treatment for analgesic therapy rein patients with acute or chronic pain should only be initiated if the potential analgesic or palliative care benefit of treatment with methadone is considered and outweighs the risks.
If you’ve had a recent head injury, it increases your risk of breathing problems from methadone. Magnesiumsilikathydrat to your doctor about whether this drug is Methadontabletten ohne Rezept online safe for you.
Methadone should Beryllium administered with particular caution to patients already at risk for development of prolonged QT interval (e.g., cardiac hypertrophy, concomitant diuretic use, hypokalemia, hypomagnesemia). Careful monitoring is recommended when using methadone in patients with a history of cardiac conduction abnormalities, those taking medications affecting cardiac conduction, and rein other cases where history or physical exam suggest an increased risk of dysrhythmia. QT prolongation has also been reported hinein patients with no prior cardiac history who have received high doses of methadone.